| — | Among Us | White (voice) |
| — | Adventures in Wonder Park | Steve |
| — | Shatter Belt | Dervey Ryan |
| — | Absolute Dominion | |
| 2024 | Ghostbusters: Frozen Empire | Dr. Hubert Wartzki |
| 2024 | Manhunt | Det. Lafayette Baker |
| 2024 | Grimsburg | Slasher (voice) |
| 2024 | Grimsburg | (voice) |
| 2024 | John Mulaney Presents: Everybody's in L.A. | Self |
| 2024 | After Midnight | Self |
| 2024 | The 1% Club | Self - Host |
| 2024 | Drew Friedman: Vermeer of the Borscht Belt | Self |
| 2024 | Blake Edwards: A Love Story in 24 Frames | |
| 2024 | Chain Reactions | Self |
| 2023 | 80 for Brady | Brisket |
| 2023 | Heroes of the Golden Masks | Aesop (voice) |
| 2023 | A Disturbance in the Force: How the Star Wars Holiday Special Happened | Self |
| 2023 | Unicorn Boy | King Uniturius (voice) |
| 2022 | The Sandman | Matthew the Raven (voice) |
| 2022 | Weird: The Al Yankovic Story | Heckler |
| 2022 | Minions & More Volume 2 | Max (voice) |
| 2022 | Gaslit | Chuck Colson |
| 2022 | I Love My Dad | Chuck |
| 2022 | George Carlin's American Dream | Self |
| 2022 | The Jennifer Hudson Show | Self |
| 2022 | Patton Oswalt: We All Scream | Self |
| 2022 | StoryBots: Answer Time | Super Snowy Icy Cone Guy |
| 2022 | Dark Side of Comedy | Self |
| 2022 | Mystery Science Theater 3000 | Max "Tv's Son of Tv's Frank" |
| 2022 | Celebrity Jeopardy! | Self |
| 2022 | MEAD | MEAD (voice) |
| 2022 | Mike Mignola: Drawing Monsters | Self |
| 2021 | Eternals | Pip the Troll (voice) |
| 2021 | Inside Job | TSA Guard (voice) |
| 2021 | Marvel's M.O.D.O.K. | George Tarleton / M.O.D.O.K. (voice) |
| 2021 | Reno 911!: The Hunt for QAnon | Ron |
| 2021 | The Sparks Brothers | Self |
| 2021 | The Spine of Night | Pyrantin |
| 2021 | The Ghost and Molly McGee | Mayor Brunson (voice) |
| 2021 | The Super Bob Einstein Movie | Self |
| 2021 | Penguin Town | Self |
| 2021 | Celebrity Wheel of Fortune | Self - Contestant |
| 2021 | Teenage Euthanasia | |
| 2021 | (OFFICIAL) THE KING OF QUEENS REUNION - FULL CAST TABLE READ | Q&A | TRIBUTE TO JERRY STILLER | Himself |
| 2021 | Monty Python's Best Bits Celebrated | Self |
| 2020 | Star Trek: Picard | Spot 73 (voice) |
| 2020 | We Bare Bears: The Movie | Nom Nom (voice) |
| 2020 | Space Force | Captain Lancaster |
| 2020 | I'll Be Gone in the Dark | Self - Michelle's Husband |
| 2020 | Patton Oswalt: I Love Everything | Self |
| 2020 | Best of Stand-up 2020 | Self |
| 2020 | Home Movie: The Princess Bride | Vizzini |
| 2020 | Reno 911! | Max Logan (voice) |
| 2020 | Reno 911! | Max Logan |
| 2020 | A Virtual Princess Bride Reunion | Moderator |
| 2020 | In Deep With Ryan Lochte | Narrator |
| 2020 | The Priest | Father Shauna |
| 2019 | The Boys | Patton Oswalt (uncredited) |
| 2019 | The Secret Life of Pets 2 | Max (voice) |
| 2019 | What We Do in the Shadows | Patton Oswalt |
| 2019 | Kim Possible | Professor Dementor |
| 2019 | Bless the Harts | Vohnnie Ray Power |
| 2019 | A Little Late with Lilly Singh | Self |
| 2019 | Dads | Self |
| 2019 | Tamron Hall | Self - Guest |
| 2019 | Super Gidget | Max (voice) |
| 2019 | Lights Out with David Spade | Self - Panelist |
| 2019 | You're Not a Monster | Invisible Man |
| 2019 | Adams | Roger |
| 2018 | Sorry to Bother You | Mr. _______'s White Voice (voice) |
| 2018 | Teen Titans Go! To the Movies | Atom (voice) |
| 2018 | Please Stand By | Officer Frank |
| 2018 | A.P. Bio | Principal Ralph Durbin |
| 2018 | The Conners | Don Blansky |
| 2018 | Spy Kids: Mission Critical | |
| 2018 | Nostalgia | Kathleen's Father |
| 2018 | Minecraft: Story Mode | Jesse (male voice) |
| 2018 | Blark and Son | Mr. Beal (voice) |
| 2018 | We Brought Back MST3K | Self |
| 2018 | Monster Challenge | Himself |
| 2018 | Sex Madness Revealed | Jimmy Morris |
| 2017 | The Circle | Tom Stenton |
| 2017 | Santa Clarita Diet | Dr. Hasmedi |
| 2017 | HAPPY! | Happy (voice) |
| 2017 | Marvel's Spider-Man | Uncle Ben (voice) |
| 2017 | Big Hero 6 The Series | Mr. Sparkle / Dispatch Voice (voice) |
| 2017 | Big Hero 6 The Series | Mr. Sparkle (voice) |
| 2017 | Will & Grace | Danley Walker |
| 2017 | Dimension 404 | Uncle Dusty |
| 2017 | Patton Oswalt: Annihilation | Self |
| 2017 | Gilbert | Self |
| 2017 | Mystery Science Theater 3000 | Max (TV's Son of TV's Frank) |
| 2017 | I Love You, America | Self |
| 2017 | The History of Comedy | Self |
| 2017 | Click, Clack, Moo: Christmas at the Farm | Appliance Al (voice) |
| 2016 | Keeping Up with the Joneses | Bruce Springstein / Scorpion |
| 2016 | The Confirmation | Drake |
| 2016 | Donald Trump's The Art of the Deal: The Movie | Merv Griffin |
| 2016 | Justice League Action | Space Cabbie (voice) |
| 2016 | Full Frontal with Samantha Bee | Self |
| 2016 | Patton Oswalt: Talking for Clapping | Himself |
| 2016 | Lady Dynamite | Patton Cop |
| 2016 | Nerdland | Elliot (voice) |
| 2016 | HarmonQuest | Sand Pole |
| 2016 | Zoolander: Super Model | Dr. Botoxo (voice) |
| 2016 | Bajillion Dollar Propertie$ | Derek Young |
| 2016 | To Tell the Truth | Self - Panelist |
| 2016 | Neil Gaiman: Dream Dangerously | Self |
| 2016 | Laurie Kilmartin: 45 Jokes About My Dead Dad | Himself |
| 2015 | We Bare Bears | Nom Nom / Additional Voices (voice) |
| 2015 | We Bare Bears | Nom Nom (voice) |
| 2015 | Freaks of Nature | Stuart Miller |
| 2015 | The Late Show with Stephen Colbert | |
| 2015 | The Late Show with Stephen Colbert | Self |
| 2015 | Crazy Ex-Girlfriend | J. Castleman |
| 2015 | Dude Bro Party Massacre III | Chief |
| 2015 | Battle Creek | Mayor Hardy |
| 2015 | The Adventures of Puss in Boots | Francisco (voice) |
| 2015 | Call Me Lucky | Self |
| 2015 | Difficult People | Kenny Jurgens |
| 2015 | Chronic-Con, Episode 420: A New Dope | Himself |
| 2015 | Pig Goat Banana Cricket | Jimmy Ron Cricket (voice) |
| 2015 | The Loneliest Stoplight | Narrator (voice) |
| 2015 | Welcome to Bridgetown | Himself |
| 2014 | 22 Jump Street | MC State History Professor (uncredited) |
| 2014 | BoJack Horseman | Charlie Rose / Pinky Penguin / Doctor (voice) |
| 2014 | BoJack Horseman | Neal McBeal (voice) |
| 2014 | BoJack Horseman | Pinky Penguin / Gary / Maggot Funeral Director (voice) |
| 2014 | BoJack Horseman | Pinky Penguin / Laughing Crew Member (voice) |
| 2014 | BoJack Horseman | Pinky Penguin (voice) |
| 2014 | BoJack Horseman | Pinky Penguin / Crab Guy (voice) |
| 2014 | BoJack Horseman | David / Pig Doctor (voice) |
| 2014 | BoJack Horseman | Dr. Pepin (Walnut Springs) (voice) |
| 2014 | BoJack Horseman | Pinky Penguin / Comedian (voice) |
| 2014 | BoJack Horseman | Pig Doctor (voice) |
| 2014 | The Tonight Show Starring Jimmy Fallon | Self |
| 2014 | The Tonight Show Starring Jimmy Fallon | |
| 2014 | Late Night with Seth Meyers | Self |
| 2014 | Harmontown | Self |
| 2014 | Marvel: 75 Years, from Pulp to Pop! | Self |
| 2014 | Patton Oswalt: Tragedy Plus Comedy Equals Time | Self |
| 2014 | Sex and Broadcasting | Himself |
| 2014 | TripTank | Pegasus (voice) |
| 2014 | Out of Print | Self |
| 2014 | Jason Nash Is Married | Producer |
| 2014 | Off Camera with Sam Jones | Self |
| 2014 | Lemonade War | Jerry |
| 2014 | We the Economy: 20 Short Films You Can't Afford to Miss | Lemonade Stand Dad |
| 2013 | Rick and Morty | Beta 7 (voice) |
| 2013 | The Secret Life of Walter Mitty | Todd Maher |
| 2013 | Marvel's Agents of S.H.I.E.L.D. | Eric Koenig |
| 2013 | Marvel's Agents of S.H.I.E.L.D. | Billy Koenig |
| 2013 | Marvel's Agents of S.H.I.E.L.D. | Billy Koenig / Sam Koenig |
| 2013 | Marvel's Agents of S.H.I.E.L.D. | Billy Koenig / Sam Koenig / Thurston Koenig |
| 2013 | Marvel's Agents of S.H.I.E.L.D. | Ernest Koenig |
| 2013 | Brooklyn Nine-Nine | Fire Marshall Boone |
| 2013 | Odd Thomas | Ozzie P. Boone |
| 2013 | Orphan Black | Self |
| 2013 | The Goldbergs | Adam Goldberg (voice) |
| 2013 | Drunk History | Mac Brazel |
| 2013 | Mighty Med | Ed / The Extrminator |
| 2013 | Mighty Med | Ed |
| 2013 | @midnight with Chris Hardwick | Self |
| 2013 | The Walking Dead: A Decade of Dead | Himself |
| 2013 | The Jeselnik Offensive | Self |
| 2013 | Radiolab Live: Apocalyptical | Himself |
| 2012 | Gravity Falls | Franz (voice) |
| 2012 | Seeking a Friend for the End of the World | Roache |
| 2012 | Veep | Teddy Sykes |
| 2012 | Comedians in Cars Getting Coffee | Self |
| 2012 | Nature Calls | Randy Stevens |
| 2012 | Comedy Bang! Bang! | Self |
| 2012 | The Bitter Buddha | Himself |
| 2012 | Viva Lucha Libre | Himself |
| 2011 | Young Adult | Matt Freehauf |
| 2011 | A Very Harold & Kumar Christmas | Mall Santa |
| 2011 | Bob's Burgers | Moody Foodie (voice) |
| 2011 | Portlandia | Thor83 |
| 2011 | Billy on the Street | Self |
| 2011 | Patton Oswalt: Finest Hour | Himself |
| 2011 | Warren Ellis: Captured Ghosts | Self |
| 2011 | The Heart, She Holler | Hurlan |
| 2011 | Who the F#ck Is Chip Seinfeld? | Self |
| 2010 | Justified | Bob Sweeney |
| 2010 | My Little Pony: Friendship Is Magic | Quibble Pants (voice) |
| 2010 | Caprica | Baxter Sarno |
| 2010 | Raising Hope | Rubin |
| 2010 | Conan | Self |
| 2010 | Blood Into Wine | Himself |
| 2010 | Weird: The Al Yankovic Story | Dr. Demento |
| 2010 | Neighbors from Hell | Pazuzu |
| 2010 | Beautiful Darling | Andy Warhol (voice) / Truman Capote (voice) |
| 2010 | Robotomy | |
| 2010 | Fantasia in Best Show Minor | |
| 2009 | Modern Family | Ducky |
| 2009 | Community | Male Nurse Jackie |
| 2009 | Parks and Recreation | Self |
| 2009 | Parks and Recreation | Garth Blundin |
| 2009 | Archer | Alan Shapiro (voice) |
| 2009 | The Informant! | Ed Herbst |
| 2009 | Observe and Report | Toast A Bun Manager |
| 2009 | Dollhouse | Joel Mynor |
| 2009 | United States of Tara | Neil |
| 2009 | Big Fan | Paul Aufiero |
| 2009 | Watch What Happens Live with Andy Cohen | Self - Guest |
| 2009 | Patton Oswalt: My Weakness Is Strong | Himself |
| 2009 | Funny People: Live | Self |
| 2009 | Al's Brain | Co-Worker |
| 2008 | All Roads Lead Home | Milo |
| 2008 | Lewis Black's Root of All Evil | Self |
| 2008 | History of the Joke | Self |
| 2008 | Largo | Himself |
| 2007 | Ratatouille | Remy (voice) |
| 2007 | Wrong Turn 2: Dead End | Tommy (voice) |
| 2007 | Balls of Fury | Hammer |
| 2007 | Burn Notice | Calvin Schmidt |
| 2007 | Your Friend the Rat | Remy (voice) |
| 2007 | Flight of the Conchords | Elton John Impersonator |
| 2007 | Sex and Death 101 | Fred |
| 2007 | Reno 911!: Miami | Jeff Spoder |
| 2007 | Reaper | |
| 2007 | Super High Me | Himself |
| 2007 | Tim and Eric Awesome Show, Great Job! | Beaver Boys Doctor |
| 2007 | Tim and Eric Awesome Show, Great Job! | Joshua Beard |
| 2007 | Tim and Eric Awesome Show, Great Job! | Joshua Beard (uncredited) |
| 2007 | The Sarah Silverman Program. | Vincent Van Guy |
| 2007 | Heckler | Self |
| 2007 | Comedy Central Roast of Flavor Flav | Self |
| 2007 | Human Giant | Let's Go Fan |
| 2007 | WordGirl | Tobey McCalister III (voice) |
| 2007 | The Comedians of Comedy: Live at The Troubadour | Himself |
| 2007 | Patton Oswalt: Werewolves and Lollipops | Himself |
| 2007 | The Sophisticated Misfit | Himself |
| 2006 | Failure to Launch | Techie Guy |
| 2006 | Comedy Central Roast of William Shatner | Self - Roaster |
| 2006 | The Amazing Screw-On Head | Mr. Groin (voice) |
| 2006 | The Comedians of Comedy: Live at the El Rey | Himself |
| 2006 | Last Laugh '06 | Himself |
| 2006 | Amazing Screw-On Head | |
| 2006 | Live at Gotham | Self |
| 2005 | American Dad! | Cinema Ticket Man (voice) |
| 2005 | American Dad! | Candy Maker (voice) |
| 2005 | American Dad! | Kiss Cam Operator (voice) |
| 2005 | American Dad! | Rick Rod (voice) |
| 2005 | American Dad! | (voice) |
| 2005 | The Comedians of Comedy | Himself |
| 2005 | Last Laugh '05 | Self |
| 2005 | Comedians of Comedy | Himself |
| 2005 | Cake Boy | Cake Pervert |
| 2005 | Too Late with Adam Carolla | |
| 2004 | Blade: Trinity | Hedges |
| 2004 | Starsky & Hutch | Disco DJ |
| 2004 | Taxi | Clerk at Inpound Office |
| 2004 | Veronica Mars | Penn Epner |
| 2004 | The Batman | Cosmo Krank (voice) |
| 2004 | The Batman | Marty Slack (voice) |
| 2004 | The Venture Bros. | Wonderboy (voice) |
| 2004 | Squidbillies | Talking Squid (voice) |
| 2004 | Tom Goes to the Mayor | Zynx (voice) |
| 2004 | Patton Oswalt: No Reason to Complain | Himself |
| 2004 | Best Week Ever | |
| 2004 | See This Movie | Felix |
| 2004 | Toro and Moro | Jerry |
| 2003 | Two and a Half Men | Billy Stanhope |
| 2003 | Calendar Girls | Larry |
| 2003 | Real Time with Bill Maher | Himself |
| 2003 | Jimmy Kimmel Live! | Self |
| 2003 | Reno 911! | |
| 2003 | Reno 911! | Dungeon Master |
| 2003 | Reno 911! | Kenny Rogers Assassin |
| 2003 | Comedy Central Roasts | Self |
| 2002 | Kim Possible | Professor Dementor (voice) |
| 2002 | Kim Possible | Professor DeMenz (voice) |
| 2002 | Run Ronnie Run | Dozer - Editor #1 |
| 2002 | Zig Zag | Shelly |
| 2001 | Zoolander | Monkey Photographer |
| 2001 | The Fairly OddParents | Crimson Chin Writer |
| 2000 | Curb Your Enthusiasm | Harry Baskin |
| 2000 | Static Shock | Specs (voice) |
| 2000 | Static Shock | Specs / Spectral (voice) |
| 2000 | Aqua Teen Hunger Force | |
| 2000 | Aqua Teen Hunger Force | Ezekial (voice) |
| 2000 | Desperate But Not Serious | Auteur #1 |
| 1999 | Family Guy | Tyler (voice) |
| 1999 | Family Guy | Bear Show Manager (voice) |
| 1999 | Magnolia | Delmer Darion |
| 1999 | Futurama | Unattractive Giant Monster (voice) |
| 1999 | Man on the Moon | Blue Collar Guy |
| 1999 | Batman Beyond | Eldon Michaels (voice) |
| 1999 | Home Movies | |
| 1999 | The N.Y. Friars Club Roast of Jerry Stiller | Self |
| 1998 | The King of Queens | Spence Olchin |
| 1998 | Comedy Central Presents | |
| 1998 | Hollywood Squares | |
| 1998 | HBO Comedy Half-Hour: Patton Oswalt | |
| 1997 | The Weird Al Show | Seymour |
| 1997 | Emeril Live | |
| 1996 | The Daily Show | Self |
| 1996 | Down Periscope | Stingray Radioman |
| 1995 | MADtv | Crip in Wheelchair |
| 1995 | NewsRadio | Guy |
| 1995 | Dr. Katz, Professional Therapist | |
| 1995 | HBO Comedy Half Hour | Self |
| 1993 | Late Night with Conan O'Brien | Self - Guest |
| 1992 | The Tonight Show with Jay Leno | |
| 1989 | The Simpsons | Bart's Guilt (voice) |
| 1989 | The Simpsons | T-Rex (voice) / Bart's guilt (voice) |
| 1989 | Seinfeld | Clerk |
| 1989 | Mystery Science Theater 3000 | Max / TV's Son of TV's Frank |
