| — | Micro Budget | Darby |
| 2024 | The People's Joker | Lorne Michaels (voice) |
| 2024 | Kite Man: Hell Yeah! | Baby Doll / Little Girl / Mom 1 (voice) |
| 2024 | Kite Man: Hell Yeah! | Baby Doll / Mother (voice) |
| 2024 | After Midnight | Self |
| 2023 | Quiz Lady | Marybeth Windlemore |
| 2023 | Adventure Time: Fionna & Cake | Starchy (voice) |
| 2023 | Adventure Time: Fionna & Cake | Farmworld Mom / Wildberry / Finn's Kid #1 (voice) |
| 2023 | Adventure Time: Fionna & Cake | Banana Guard Mutant #1 (voice) |
| 2023 | Adventure Time: Fionna & Cake | Additional Voices (voice) |
| 2023 | Maria Bamford: Local Act | Self |
| 2023 | Unicorn Boy | Queen Junipero (voice) |
| 2022 | The Bubble | Krystal's Mom |
| 2022 | Human Resources | Tito the Anxiety Mosquito (voice) |
| 2022 | Human Resources | Tito Taylor Thomas / Kitty Dukakis / Becca's Need Demon (voice) |
| 2022 | Dark Side of Comedy | Self |
| 2021 | Extinct | Bo's Mom (voice) |
| 2021 | Centaurworld | Malangella / Maitre D / Opposumtaur (voice) |
| 2021 | Centaurworld | Malangella (voice) |
| 2021 | Mr. Mayor | Leaf |
| 2021 | Santa Inc. | Mrs. Claus / Big Candy (voice) |
| 2021 | Kenan | Glory |
| 2021 | Ultra City Smiths | Genia Myers |
| 2021 | I Heart Arlo | Aunt Guy (voice) |
| 2021 | I Heart Arlo | Cop (voice) |
| 2021 | I Heart Arlo | Granny (voice) |
| 2021 | I Heart Arlo | Wife (voice) / Kids (voice) / Walla (voice) |
| 2021 | I Heart Arlo | Tony's Mom (voice) / Family (voice) / Cats (voice) |
| 2021 | I Heart Arlo | Garbage Collector 2 (voice) |
| 2021 | I Heart Arlo | Bortie (voice) |
| 2021 | Flatbush Misdemeanors | Maria |
| 2021 | Teenage Euthanasia | Trophy Fantasy (voice) |
| 2021 | Too Many Buddhas | Dr. Stevens |
| 2020 | Animaniacs | Tammy (voice) |
| 2020 | Animaniacs | Julia (voice) |
| 2020 | Adventure Time: Distant Lands | Margaret (voice) |
| 2020 | Adventure Time: Distant Lands | Sandy (voice) |
| 2020 | Seven Stages to Achieve Eternal Bliss | Cultist |
| 2020 | Maria Bamford: Weakness Is the Brand | Herself |
| 2020 | This Is Stand-Up | Self |
| 2019 | The Mind, Explained | Herself |
| 2019 | The Mind, Explained | Self |
| 2019 | Still Laugh-In: The Stars Celebrate | Self |
| 2019 | Victor and Valentino | Guadelupe (voice) |
| 2019 | The Rocketeer | Laura (voice) |
| 2019 | Lights Out with David Spade | Self - Panelist |
| 2019 | Strong Independent Women | Mom |
| 2019 | Debbie & Doug Drop Acid in the Desert | Ariel |
| 2019 | What's Your Ailment?! | Self |
| 2018 | An Evening with Beverly Luff Linn | The Elegant Woman |
| 2018 | The Shivering Truth | (voice) |
| 2018 | Summer Camp Island | Puffer Fish (voice) |
| 2018 | Summer Camp Island | The Royal Mush (voice) |
| 2018 | Summer Camp Island | Toothpaste (voice) |
| 2018 | Summer Camp Island | Foghorn (voice) |
| 2018 | Summer Camp Island | Polly (voice) |
| 2018 | Summer Camp Island | Sandy (voice) |
| 2018 | Liverspots and Astronots | Abrams |
| 2017 | Big Mouth | Tito the Anxiety Mosquito (voice) |
| 2017 | Big Mouth | |
| 2017 | Puss in Book: Trapped in an Epic Tale | The Duchess (voice) |
| 2017 | Maria Bamford: Old Baby | |
| 2017 | The History of Comedy | Self |
| 2016 | Lady Dynamite | Maria Bamford |
| 2016 | Dream Corp LLC | Norf Norf (voice) |
| 2016 | Ask the Storybots | |
| 2016 | A Little of Your Time with Quinn Marcus | Herself |
| 2015 | We Bare Bears | Miss Chriss (voice) |
| 2015 | Star vs. the Forces of Evil | Make-Up Blast (voice) |
| 2015 | The Late Show with Stephen Colbert | Self |
| 2015 | Fresh Off the Boat | Principal Thomas |
| 2015 | Hell & Back | Gloria (voice) |
| 2015 | The Adventures of Puss in Boots | The Duchess (voice) |
| 2015 | The Adventures of Puss in Boots | Feejee (voice) |
| 2015 | The Adventures of Puss in Boots | The Duchess / Feejee (voice) |
| 2015 | Misery Loves Comedy | Self |
| 2015 | Harvey Beaks | Grada (voice) |
| 2014 | BoJack Horseman | Kelsey Jannings (voice) |
| 2014 | BoJack Horseman | Kelsey Jannings / Debra (voice) |
| 2014 | BoJack Horseman | Kelsey Jannings / Fan / Customer (voice) |
| 2014 | Clarence | Dilliss (voice) |
| 2014 | Late Night with Seth Meyers | Self |
| 2014 | Benched | Sheryl |
| 2014 | Talking Tom and Friends | Ginger (voice) |
| 2014 | Penn Zero: Part-Time Hero | The President (voice) |
| 2014 | Penn Zero: Part-Time Hero | Matthews (voice) |
| 2014 | Penn Zero: Part-Time Hero | Mrs. Monkenfluffer (voice) |
| 2014 | Penn Zero: Part-Time Hero | Nug (voice) |
| 2014 | Penn Zero: Part-Time Hero | Mrs. Monkenfluffer / Matthews (voice) |
| 2014 | Penn Zero: Part-Time Hero | Land Shark (voice) |
| 2014 | I Am Road Comic | Self |
| 2014 | Dead End | Pauline |
| 2014 | Play Nice | |
| 2013 | Rick and Morty | (voice) |
| 2013 | @midnight with Chris Hardwick | Self |
| 2013 | Have You Been Paying Attention? | Self - Panellist |
| 2013 | Timms Valley | Genia Myers |
| 2013 | DC Nation - Tales of Metropolis - "Bizarro" | Lois Lane (voice) |
| 2013 | DC Nation - Tales of Metropolis - "Lois" | Lois Lane (voice) |
| 2012 | The Legend of Korra | Pema (voice) |
| 2012 | Comedy Bang! Bang! | Claire Coulter |
| 2012 | Bravest Warriors | Lydia (voice) |
| 2012 | Unsupervised | Rachel / Megan's Mom / Sid's Wife (voice) |
| 2012 | Unsupervised | Allie (voice) |
| 2012 | Unsupervised | Rachel / Ms. Davis (voice) |
| 2012 | Unsupervised | Megan's Mom (voice) |
| 2012 | Unsupervised | Audrey Coates (voice) |
| 2012 | Unsupervised | Andrew's Mom (voice) |
| 2012 | Maria Bamford: The Special Special Special! | Herself |
| 2012 | DC Nation Shorts | Robin Robin / Batcow (voice) |
| 2012 | DC Nation Shorts | Robin Robin (voice) |
| 2012 | Super F*ckers | Princess Sunshine |
| 2012 | From Nothing, Something: A Documentary on the Creative Process | |
| 2012 | WordGirl: The Rise of Ms. Power | |
| 2011 | Bob's Burgers | Kendra / Catherine (voice) |
| 2011 | Kung Fu Panda: Legends of Awesomeness | Chen (voice) |
| 2010 | Adventure Time | Manfried / Chocoberry / Candy Corn Girl (voice) |
| 2010 | Ugly Americans | Dolores (voice) |
| 2010 | Ugly Americans | Additional Voices (voice) |
| 2010 | Ugly Americans | Galen (voice) |
| 2010 | Kick Buttowski: Suburban Daredevil | Jackie (voice) |
| 2010 | Conan | Self |
| 2010 | Check It Out! with Dr. Steve Brule | Cynthia Driscoll |
| 2010 | Held Up | Rachel Gonzales |
| 2010 | Maria Bamford: Plan B | Self |
| 2010 | Danger Planet | Captain |
| 2009 | Sit Down Shut Up | Mrs. Grohe |
| 2009 | Sit Down Shut Up | Actress in School Play |
| 2009 | Sit Down Shut Up | Marie Dembowitz |
| 2009 | Funny People: Live | Self |
| 2009 | Comedy.tv | |
| 2009 | Maria Bamford's One-Hour Homemade Christmas Stand-up Special | Herself |
| 2009 | Maruined | Zack |
| 2009 | The Room Before and After - Part 3: Maria Bamford | |
| 2007 | Back at the Barnyard | Nora Beady |
| 2007 | Tim and Eric Awesome Show, Great Job! | TV Host |
| 2007 | Tim and Eric Awesome Show, Great Job! | Candy Tails Commercial Announcer (voice) |
| 2007 | Tim and Eric Awesome Show, Great Job! | Maria the Cat Specialist |
| 2007 | The Sarah Silverman Program. | May Kadoody |
| 2007 | Heckler | Self |
| 2007 | WordGirl | Violet (voice) |
| 2007 | The Comedians of Comedy: Live at The Troubadour | Self |
| 2006 | Barnyard | Mrs. Beady (voice) |
| 2006 | The Comedians of Comedy: Live at the El Rey | Self |
| 2006 | Where My Dogs At? | |
| 2006 | Just for Laughs Stand Up, Vol. 2: On the Edge | Self |
| 2006 | Comics Unleashed | Self |
| 2005 | The Late Late Show with Craig Ferguson | Self |
| 2005 | The Comedians of Comedy | Self |
| 2005 | Coconut Fred's Fruit Salad Island | Melody |
| 2005 | Coconut Fred's Fruit Salad Island | The Waiting Lady |
| 2005 | Comedians of Comedy | Self |
| 2004 | Tom Goes to the Mayor | Home Shopping Woman / Sandy (voice) |
| 2003 | Arrested Development | Debrie |
| 2003 | Charlotte's Web 2: Wilbur's Great Adventure | Aranea (voice) |
| 2003 | Hey Monie! | Sex Education Teacher |
| 2002 | Stuart Little 2 | Teacher |
| 2002 | ¡Mucha Lucha! | |
| 2000 | Lucky Numbers | Wendy |
| 2000 | CatDog and the Great Parent Mystery | Shriek Dubois (voice) |
| 2000 | The Trouble with Normal | Dora |
| 2000 | Hairballs | (voice) |
| 1999 | Home Movies | |
| 1999 | Los Enchiladas! | Sarah |
| 1998 | CatDog | Shriek (voice) |
| 1998 | Comedy Central Presents | |
| 1998 | Fetch | Shriek |
| 1997 | Dharma & Greg | Sandy |
| 1997 | The Tom Show | Christy |
| 1996 | Hey Arnold! | Iggy's Mother (voice) |
| 1996 | Hey Arnold! | Mayor Dixie (voice) |
| 1996 | Hey Arnold! | Mayor Dixie / Stinky's Grandma (voice) |
