| — | How to Stop Time | Tom |
| — | Gypsy Boy | |
| 2026 | Avengers: Doomsday | Stephen Strange / Doctor Strange |
| — | Rogue Male | |
| — | The Phoenician Scheme | Uncle Nubar |
| — | The War Magician | Jasper Maskelyne |
| — | Doctor Strange 3 | Stephen Strange / Doctor Strange |
| — | The Roses | Theo |
| — | Rio | |
| — | The Hood | |
| — | Magik | Lewis |
| — | Morning | Frank |
| — | The Thing With Feathers | |
| — | The 39 Steps | Richard Hannay |
| — | Sherlock | Sherlock Holmes |
| — | Have I Got a Bit More News for You | Self - Presenter |
| 2024 | Eric | Vincent |
| 2024 | The Book of Clarence | Benjamin |
| 2024 | Minunata povestire a lui Henry Sugar și încă trei | Henry Sugar / Max Engelman / Harry |
| 2023 | Minunata povestire a lui Henry Sugar | Henry Sugar / Max Engelman |
| 2023 | Otrava | Harry Pope |
| 2023 | The End We Start From | AB |
| 2023 | Mog's Christmas | Mr. Thomas (voice) |
| 2023 | Arctic: Our Frozen Planet | Narrator |
| 2022 | Doctor Strange în Multiversul Nebuniei | Doctor Stephen Strange |
| 2022 | Minions & More 1 | The Grinch (voice) |
| 2022 | Spider-Man: All Roads Lead to No Way Home | Self (archive footage) |
| 2022 | Marvel Studios Assembled: The Making of Doctor Strange in the Multiverse of Madness | Self - Doctor Stephen Strange |
| 2022 | Super/Natural | Self - Narrator (voice) |
| 2022 | Behind the Scenes With Jane Campion | Self (archive footage) |
| 2022 | Vedete în sălbăticie, cu Bear Grylls: Provocarea | Self |
| 2022 | The Tiger Who Came to Tea | Daddy (voice) |
| 2022 | Reframing the West: Behind the Scenes of Jane Campion's The Power of the Dog | |
| 2021 | Omul-Păianjen: Niciun drum spre casă | Doctor Strange |
| 2021 | Și dacă...? | Doctor Strange (voice) |
| 2021 | Și dacă...? | Doctor Strange / Strange Supreme (voice) |
| 2021 | Și dacă...? | Doctor Strange / Strange-Supreme (voice) |
| 2021 | Și dacă...? | Strange Supreme / Demon Strange (voice) |
| 2021 | Puterea câinelui | Phil Burbank |
| 2021 | Mauritanul | Lt. Stuart Couch |
| 2021 | Legendele studiourilor Marvel | Stephen Strange / Doctor Strange (archive footage) |
| 2021 | Viața electrizantă a lui Louis Wain | Louis Wain |
| 2021 | Marvel Studios' 2021 Disney+ Day Special | Stephen Strange / Doctor Strange (voice) (archive footage) |
| 2021 | Letters Live from the Archive: Freemasons’ Hall | |
| 2021 | Letters Live from the Archive: Union Chapel | Self |
| 2020 | Umbra spionului | Greville Wynne |
| 2020 | Chadwick Boseman: A Tribute for a King | Self |
| 2020 | Antarctica | Self - Narrator |
| 2019 | Răzbunătorii: Sfârșitul jocului | Doctor Strange |
| 2019 | 1917: Speranță și moarte | Colonel MacKenzie |
| 2019 | Good Omens | Satan (voice) |
| 2019 | Between Two Ferns: The Movie | Benedict Cumberbatch |
| 2019 | Brexit | Dominic Cummings |
| 2019 | The Kelly Clarkson Show | |
| 2019 | The Dog Days of Winter | The Grinch (voice) |
| 2019 | Cindy-Lou's Yule Log | The Grinch |
| 2018 | Răzbunătorii: Războiul infinitului | Doctor Strange |
| 2018 | Grinch | Grinch (voice) |
| 2018 | Mowgli: Legenda junglei | Shere Khan (voice) |
| 2018 | The Current War | Thomas Edison |
| 2018 | Patrick Melrose | Patrick Melrose |
| 2018 | The Child in Time | Stephen Lewis |
| 2018 | The Grinch Mini-Movies | Grinch (voice) |
| 2017 | Thor: Ragnarok | Doctor Strange |
| 2017 | Walk with Me | Narrator (voice) |
| 2016 | Doctor Strange | Dr. Stephen Strange |
| 2016 | Sherlock: The Abominable Bride | Sherlock Holmes |
| 2016 | Zoolander 2 | All |
| 2016 | Shakespeare Live! From the RSC | Self - Performer |
| 2016 | Naples '44 | Norman Lewis (voice) |
| 2016 | Mark Gatiss: A Study in Sherlock | Himself |
| 2015 | Black Mass: Afaceri murdare | Billy Bulger |
| 2015 | National Theatre Live: Hamlet | Hamlet |
| 2014 | Jocul codurilor | Alan Turing |
| 2014 | Hobbitul: Bătălia celor cinci oștiri | Smaug / Sauron (voice) |
| 2014 | Pinguinii din Madagascar | Classified (voice) |
| 2014 | Emisiunea din seara asta cu Jimmy Fallon | Self |
| 2014 | Emisiunea din seara asta cu Jimmy Fallon | |
| 2014 | Late Night with Seth Meyers | Self |
| 2014 | Cristiano Ronaldo: World at His Feet | Narrator |
| 2014 | 9 săruturi | Man at Costume Party |
| 2014 | Unlocking Sherlock | Himself / Sherlock Holmes |
| 2014 | The Penguins of Madagascar: Operation Search and Rescue | Agent Classified |
| 2014 | Variety Studio: Actors on Actors | Self |
| 2014 | Walking with Dinosaurs: Prehistoric Planet 3D | Narrator (Voice) |
| 2013 | Hobbitul: Dezolarea lui Smaug | Smaug / Sauron |
| 2013 | 12 ani de sclavie | William Ford |
| 2013 | Star Trek: În întuneric | John Harrison / Khan |
| 2013 | Ținutul din mijlocul verii | Little Charles Aiken |
| 2013 | The Fifth Estate | Julian Assange |
| 2013 | Pe urmele dinozaurilor | Narrator (Prehistoric Planet 3D Version) |
| 2013 | Ierusalim | Narrator (voice) |
| 2013 | Little Favour | Wallace |
| 2013 | Sherlock: Many Happy Returns | Sherlock Holmes |
| 2013 | National Theatre Live: 50 Years on Stage | Rosencrantz |
| 2013 | Solar Superstorms | Narrator |
| 2013 | Stephen Hawking Biography | Self |
| 2012 | Hobbitul: O călătorie neașteptată | Necromancer |
| 2012 | Parade's End | Christopher Tietjens |
| 2012 | The Hollow Crown | Richard |
| 2012 | The Hollow Crown | Richard III |
| 2012 | Stephen Hawking: Marea proiectare | Narrator (voice) |
| 2012 | Girlfriend in a Coma | Dante (Voice) |
| 2012 | WWI's Tunnels of Death The Big Dig | Narrator (Voice) |
| 2012 | Frankenstein: A Modern Myth | Self / Frankenstein / The Monster |
| 2012 | Sherlock: Uncovered | Sherlock, Self |
| 2012 | 빈센트 반 고흐: 편지로 만나는 그의 삶과 그림 | |
| 2012 | YOUは何しに日本へ? | Self |
| 2011 | Calul de luptă | Maj. Jamie Stewart |
| 2011 | Un spion care știa prea multe | Peter Guillam |
| 2011 | National Theatre Live: Frankenstein | The Creature / Victor Frankenstein |
| 2011 | Wreckers | David |
| 2011 | Emisiunea lui Jonathan Ross | Self |
| 2010 | Sherlock | Sherlock Holmes |
| 2010 | Sherlock | Self |
| 2010 | Sherlock | Self / Sherlock Holmes |
| 2010 | Patru lei paralei | The Negotiator |
| 2010 | Martor și acuzator | Nick Kaufman |
| 2010 | Third Star | James |
| 2010 | În Univers cu Stephen Hawking | Stephen Hawking |
| 2010 | Van Gogh: Painted with Words | Vincent Van Gogh |
| 2010 | Burlesque Fairytales | Henry Clark |
| 2010 | Unlocking Sherlock | Himself |
| 2009 | Originea speciilor | Joseph Dalton Hooker |
| 2009 | South Pacific | Narrator (voice) |
| 2009 | Small Island | Bernard |
| 2009 | The Turning Point | Guy Burgess |
| 2008 | Cealaltă moștenitoare Boleyn | William Carey |
| 2008 | The Last Enemy | Stephen Ezard |
| 2007 | Remușcare | Paul Marshall |
| 2007 | Emisiunea lui Graham Norton | Self |
| 2007 | Emisiunea lui Graham Norton | Self - Guest |
| 2007 | Stuart: O viață spusă invers | Alexander Masters |
| 2007 | Inseparable | Joe / Charlie |
| 2006 | Flirt de nota 10 | Patrick Watts |
| 2006 | Bunăvoință uimitoare | William Pitt |
| 2006 | Emisiunea unu | Self - Guest |
| 2005 | Nathan Barley | Robin |
| 2005 | To the Ends of the Earth | Edmund Talbot |
| 2005 | Broken News | Will Parker |
| 2005 | The Man Who Predicted 9/11 | Narrator (voice) |
| 2004 | Hawking | Stephen Hawking |
| 2004 | Agatha Christie's Marple | Luke Fitzwilliam |
| 2004 | Dunkirk | Lt Jimmy Langley |
| 2003 | Jimmy Kimmel în direct! | |
| 2003 | To Kill a King | Royalist |
| 2003 | Fortysomething | Rory Slippery |
| 2003 | Cambridge Spies | Edward Hand |
| 2002 | Spooks | Jim North |
| 2002 | Tipping the Velvet | Freddy |
| 2002 | Timeshift | self |
| 2002 | Fields of Gold | Jeremy |
| 2002 | Hills Like White Elephants | The Man |
| 1997 | Vederea | Self |
| 1997 | Leute heute | Self |
| 1996 | Emisiunea zilnică cu Trevor Noah | Self |
| 1996 | Martor tăcut | Warren Reid |
| 1993 | GMTV | Self |
| 1992 | Bătaia inimii | Toby Fisher |
| 1992 | Bătaia inimii | Charles |
| 1989 | Familia Simpson | Severus Snape / Prime Minister (voice) |
| 1989 | Familia Simpson | Quilloughby (voice) |
| 1988 | LIVE with Kelly and Mark | |
| 1975 | Sâmbătă noaptea în direct | Self - Host |
| 1975 | Sâmbătă noaptea în direct | Self - Cameo (uncredited) |
| 1953 | Premiile academiei | Self |
