| 2025 | Randroid | Randroid (voice) |
| — | Fred Armisen's Guide to Music and SXSW | |
| — | Fixed | Fetch (voice) |
| 2024 | फॉलआउट | DJ Carl |
| 2024 | अनफ़्रॉस्टेड | Mike Puntz |
| 2024 | थेल्मा द यूनिकॉर्न | Danny Stallion (voice) |
| 2024 | जॉन मुलैनी: Everybody's in L.A. | Self |
| 2024 | Come and Save Me | Hugo |
| 2024 | Never Mind | Manager Cat |
| 2024 | Hang On a Second | Self |
| 2024 | Universal Basic Guys | David (voice) |
| 2023 | द सुपर मारियो ब्रदर्स मूवी | Cranky Kong (voice) |
| 2023 | Carol & the End of the World | (voice) |
| 2023 | History of the World: Part II | Glorp |
| 2023 | अस्थिर | Leslie |
| 2023 | एजेंट एल्विस | Charles Manson (voice) |
| 2023 | Royal Crackers | Brent (voice) |
| 2023 | The Contestant | Denpa Shonen Narrator (voice) |
| 2023 | Melomaniac | Himself |
| 2022 | वेडनेसडे ऐडम्स | Uncle Fester |
| 2022 | The Bubble | Darren Eigen |
| 2022 | Our Flag Means Death | Geraldo |
| 2022 | Clerks III | Auditioner |
| 2022 | Spin Me Round | Ricky |
| 2022 | Super Pumped: The Battle for Uber | Erich England |
| 2022 | Toast of Tinseltown | Russ Nightlife |
| 2022 | The Kids in the Hall: Comedy Punks | Self |
| 2021 | The Mitchells vs. The Machines | Deborahbot 5000 (voice) |
| 2021 | Schmigadoon! | Reverend Howard Layton |
| 2021 | स्पार्क्स ब्रदर्स | Self |
| 2021 | Centaurworld | Splendib / Bimbam (voice) |
| 2021 | Centaurworld | Splendib / Guard / Human Man (voice) |
| 2021 | Centaurworld | Splendib / Kittentaur / Malandrew (voice) |
| 2021 | Centaurworld | Malandrew (voice) |
| 2021 | Centaurworld | Splendib / Message Bird / Teacher Birdtaur (voice) |
| 2021 | Centaurworld | Message Bird (voice) |
| 2021 | Centaurworld | Splendib / Malandrew / Message Bird (voice) |
| 2021 | How It Ends | Young Manny |
| 2021 | Saturday Morning All Star Hits! | (voice) |
| 2021 | That's My Jam | Self - Guest |
| 2021 | Baking It | Self |
| 2021 | Too Late | Fredo Muñoz |
| 2021 | Do, Re & Mi | Juan Peacock (voice) |
| 2020 | All Together Now | Mr. Franks |
| 2020 | Unbreakable Kimmy Schmidt: Kimmy vs. the Reverend | Robert Durst / Robertina Durst |
| 2020 | Central Park | Esposito (voice) |
| 2020 | Moonbase 8 | Skip |
| 2020 | Sarah Cooper: Everything's Fine | Scooter |
| 2020 | Magnum Dopus: The Making of Jay and Silent Bob Reboot | Self |
| 2020 | The Imminent Expiration of Seth Dodson | Dr. Greengrass |
| 2020 | The Second City Presents: The Last Show Left on Earth | Self - Guest |
| 2019 | What We Do in the Shadows | Tom 'Doctor Tom' Schmidt |
| 2019 | Jay and Silent Bob Reboot | Merkin |
| 2019 | Miracle Workers | Percival Forthwind |
| 2019 | I Think You Should Leave with Tim Robinson | |
| 2019 | The House of Tomorrow | Tour Video Narrator (voice) |
| 2019 | Los Espookys | Uncle Tico |
| 2019 | Los Espookys | Tico |
| 2019 | The Kacey Musgraves Christmas Show | Self |
| 2019 | Lights Out with David Spade | Self - Panelist |
| 2019 | Brainiac: Transmissions After Zero | Himself |
| 2019 | My View: Clem Burke | Self |
| 2019 | Adams | Adams |
| 2019 | Yo La Tengo: Hanukkah 2019 - Night One | |
| 2018 | Game Over, Man! | Fred Armisen |
| 2018 | Barry | Nestor |
| 2018 | फ़ायनल स्पेस | KVN (voice) |
| 2018 | Star Wars Resistance | Lechee (voice) |
| 2018 | Forever | Oscar |
| 2018 | Fred Armisen: Standup for Drummers | The Drummer |
| 2018 | You Can Color Outside the Lines... The Big Boys | |
| 2018 | Fortune Rookie | Fred |
| 2017 | Battle of the Sexes | Rheo Blair |
| 2017 | Big Mouth | Elliot Birch (voice) |
| 2017 | The Lego Ninjago Movie | Cole (voice) |
| 2017 | The Little Hours | Bishop Bartolomeo |
| 2017 | Band Aid | Dave |
| 2017 | Take the 10 | The Driver |
| 2017 | Michael Bolton's Big, Sexy Valentine's Day Special | Peter Salanz |
| 2017 | A Christmas Story Live! | Elf |
| 2017 | कारपूल कैरिओकी : द सीरीज़ | Self |
| 2017 | The Gong Show | Self - Judge |
| 2017 | Man in the Camo Jacket | Self |
| 2017 | Night of Too Many Stars: America Unites for Autism Programs | Self |
| 2017 | David Letterman: The Kennedy Center Mark Twain Prize | Self |
| 2017 | Cabiria, Charity, Chastity | Aldo the Instructor |
| 2016 | Zoolander 2 | VIP |
| 2016 | Ordinary World | Gary |
| 2016 | Match Game | Self - Panelist |
| 2016 | Party Legends | |
| 2016 | Resurgence: It's Early Albuquerque | Terry Dudley |
| 2015 | The Last Man on Earth | Karl |
| 2015 | Superstore | Kyle |
| 2015 | Unbreakable Kimmy Schmidt | Robert Durst |
| 2015 | Unbreakable Kimmy Schmidt | Robertina Durst |
| 2015 | 7 Days in Hell | Edward Pudding |
| 2015 | Staten Island Summer | Victor |
| 2015 | The Late Late Show with James Corden | Self - Guest |
| 2015 | Man Seeking Woman | Jesus |
| 2015 | Man Seeking Woman | Tanaka (voice) |
| 2015 | Addicted to Fresno | Gerald |
| 2015 | Documentary Now! | Various Characters |
| 2015 | Looney Tunes: Rabbits Run | Speedy Gonzales |
| 2015 | Salad Days: A Decade of Punk in Washington, DC (1980-90) | Himself |
| 2015 | Close Up with The Hollywood Reporter | Self |
| 2015 | The Damned: Don't You Wish That We Were Dead | Self |
| 2015 | Long Live the Royals | Gavin, Brody |
| 2015 | Saturday Night Live: 40th Anniversary Special | Self / Stuart / Garth |
| 2015 | George and the Vacuum | George |
| 2014 | Last Week Tonight with John Oliver | Sweet Potato (voice) / Tomatillo (voice) |
| 2014 | The Tonight Show Starring Jimmy Fallon | |
| 2014 | The Tonight Show Starring Jimmy Fallon | Self - Guest |
| 2014 | Broad City | David the baby |
| 2014 | Late Night with Seth Meyers | Self |
| 2014 | Deadbeat | Janitor |
| 2014 | Elf: Buddy's Musical Christmas | Chadwick (voice) |
| 2014 | My Depression (The Up and Down and Up of It) | Pill Bottle (voice) |
| 2014 | Off Camera with Sam Jones | Self |
| 2014 | The Maya Rudolph Show | Self |
| 2014 | The Celery Incident | Various characters |
| 2013 | Brooklyn Nine-Nine | Melipnos |
| 2013 | The Smurfs 2 | Brainy Smurf (voice) |
| 2013 | The Smurfs: The Legend of Smurfy Hollow | Brainy Smurf (voice) |
| 2013 | Hollywood Game Night | Self |
| 2013 | Revenge of the Mekons | Himself |
| 2013 | AMEX Unstaged Presents: Vampire Weekend | Ian Rubbish |
| 2012 | The Dictator | Waiter / Minister |
| 2012 | Comedians in Cars Getting Coffee | Self |
| 2012 | Comedy Bang! Bang! | Self |
| 2012 | Unsupervised | Martin (voice) |
| 2012 | Finding Your Roots | Self |
| 2012 | The Secret Policeman's Ball | Self |
| 2011 | The Smurfs | Brainy Smurf (voice) |
| 2011 | New Girl | Brandon |
| 2011 | Bob's Burgers | Tommy (voice) |
| 2011 | The Looney Tunes Show | Speedy Gonzales (voice) |
| 2011 | The Smurfs: A Christmas Carol | Brainy (voice) |
| 2011 | Portlandia | Various Characters |
| 2011 | Up All Night | Gideon Kirk |
| 2011 | The Ambiguously Gay Duo: The Dark, Clenched Hole of Evil | Live-Action Lizardo |
| 2011 | Inside Portlandia | Himself |
| 2010 | Easy A | Pastor |
| 2010 | Cop Out | Russian Lawyer |
| 2010 | Ugly Americans | Larry King (voice) |
| 2010 | Cats & Dogs: The Revenge of Kitty Galore | Freidrich |
| 2010 | Conan | Self |
| 2010 | Saturday Night | Self |
| 2010 | Presidential Reunion | Barack Obama |
| 2010 | The Women of SNL | Various (archive footage) |
| 2010 | Gavin McInnes is a Fucking Asshole | Self (archive footage) |
| 2009 | Modern Family | Langham |
| 2009 | Confessions of a Shopaholic | Ryan Koenig |
| 2009 | Parks and Recreation | Raul |
| 2009 | Archer | Gustavo Calderón (voice) |
| 2009 | Post Grad | Guacanator Pitchman |
| 2009 | Late Night with Jimmy Fallon | Self |
| 2009 | Watch What Happens Live with Andy Cohen | Self - Guest |
| 2009 | Saturday Night Live: The Best of Amy Poehler | Various (archive footage) |
| 2008 | Baby Mama | Stroller Salesman |
| 2008 | The Rocker | Kerr |
| 2008 | The Promotion | Scott Fargas |
| 2008 | Saturday Night Live Weekend Update Thursday | |
| 2008 | Christmas on Mars | Philosophical and Hymn-Singing Astronaut |
| 2008 | Largo | Self |
| 2007 | Aqua Teen Hunger Force Colon Movie Film for Theaters | Time Lincoln (voice) |
| 2007 | Tim and Eric Awesome Show, Great Job! | K.J. Nutt |
| 2007 | Tim and Eric Awesome Show, Great Job! | Sal & Al's Customer |
| 2007 | Tim and Eric Awesome Show, Great Job! | Self |
| 2007 | The Sarah Silverman Program. | Taylor Magenheim |
| 2007 | Human Giant | Dr. Marker |
| 2007 | Tim and Eric Nite Live! | Dr. Pat Gordon Hall |
| 2007 | Goodbye Baby | Comic |
| 2007 | The Shooting | Cop #2 |
| 2007 | Fred Armisen Presents: Complicated Drumming Technique Jens Hannemann | Jens Hannemann |
| 2006 | Tenacious D in The Pick of Destiny | Security Guard |
| 2006 | 30 Rock | Raheem Haddad |
| 2006 | 30 Rock | Various Characters |
| 2006 | Deck the Halls | Gustave |
| 2006 | The Ex | Manny |
| 2006 | Griffin & Phoenix | |
| 2006 | Kiss Me Again | Professor Szabo |
| 2006 | Freak Show | |
| 2006 | Book Club | Himself |
| 2006 | Saturday Night Live: The Best of Saturday TV Funhouse | Self |
| 2005 | American Dad! | Derrick (voice) |
| 2005 | Deuce Bigalow: European Gigolo | Frenchman (uncredited) |
| 2005 | Robot Chicken | Archie Andrews (voice) |
| 2005 | Saturday Night Live: The Best of David Spade | |
| 2005 | Looking for a Thrill: An Anthology of Inspiration | Self |
| 2004 | Anchorman: The Legend of Ron Burgundy | Tino |
| 2004 | EuroTrip | Creepy Italian Guy |
| 2004 | Wake Up, Ron Burgundy: The Lost Movie | Tino |
| 2004 | Squidbillies | Miguel |
| 2004 | Tom Goes to the Mayor | Phillip Priest (voice) |
| 2004 | The Tony Danza Show | Self - Guest |
| 2003 | Melvin Goes to Dinner | Vesa |
| 2002 | Like Mike | New Age Dad |
| 2002 | I Am Trying to Break Your Heart: A Film About Wilco | Himself |
| 2001 | Next! | |
| 2001 | Next Caller | |
| 2000 | Curb Your Enthusiasm | Wally |
| 2000 | Aqua Teen Hunger Force | |
| 2000 | Aqua Teen Hunger Force | Robot Husband (voice) |
| 1993 | Late Night with Conan O'Brien | Self - Guest |
| 1989 | The Simpsons | Terrence (voice) |
| 1975 | Saturday Night Live | Self - Various Characters |
| 1975 | Saturday Night Live | Self - Host |
| 1975 | Saturday Night Live | Self - Cameo (uncredited) |
| 1975 | Saturday Night Live | |
| 1975 | Saturday Night Live | Criminal |
| 1975 | Saturday Night Live | Dad |
| 1975 | Saturday Night Live | Joel |
| 1975 | Saturday Night Live | Guitar Player |
| 1975 | Saturday Night Live | Police Officer |
| 1975 | Saturday Night Live | Mahmoud Ahmadinejad |
| 1975 | Saturday Night Live | Marcus |
| 1975 | Saturday Night Live | Dennis's Boss |
| 1975 | Saturday Night Live | Auctioneer |
| 1975 | Saturday Night Live | Magician |
| 1975 | Saturday Night Live | Shaman |
| 1975 | Saturday Night Live | Doctor |
| 1975 | Saturday Night Live | Member of Blue Man Group |
