| — | Viral | |
| — | Tangles: A Story About Alzheimer's, My Mother, and Me | |
| 2024 | John Mulaney Presents: Everybody’s in L.A. | Self |
| 2024 | Dinner Time Live with David Chang | Self |
| 2024 | To the Journey - Looking Back at Star Trek: Voyager | Self |
| 2024 | Stupid Pet Tricks | Self - Host |
| 2023 | Maestro | Shirley Bernstein |
| 2023 | Il était une fois un studio | Vanellope (voice) (archive footage) |
| 2023 | La folle histoire du monde II | Lieutenantman Silverman |
| 2023 | Sarah Silverman: Someone You Love | Self |
| 2023 | Albert Brooks: Defending My Life | Self |
| 2023 | No One Asked You | Self |
| 2023 | Handsome Podcast | Self |
| 2022 | Marie-moi | Parker Debbs |
| 2022 | The Bob's Burgers Movie | Ollie Pesto (voice) |
| 2022 | The Jennifer Hudson Show | Self |
| 2022 | Menorah in the Middle | Rachel Baum |
| 2022 | David Baddiel: Jews Don't Count | Self |
| 2022 | Prophets of Change | Narrator |
| 2021 | Don't Look Up : Déni cosmique | Sarah Benterman |
| 2021 | Basket spatial : une nouvelle ère | Warner Bros. Executive |
| 2021 | Santa Inc. | Candy Smalls (voice) |
| 2021 | The Super Bob Einstein Movie | Self |
| 2021 | Star Trek : 55 ans d'histoire | Self |
| 2020 | Have a Good Trip: Adventures in Psychedelics | Self |
| 2020 | Dave Chappelle: The Kennedy Center Mark Twain Prize | Self |
| 2020 | Yearly Departed | Self |
| 2020 | In Search of the Sanderson Sisters: A Hocus Pocus Hulaween Takeover | Sarah Silverman |
| 2020 | Home Movie: The Princess Bride | The Grandfather |
| 2020 | Feeding America Comedy Festival | Self |
| 2020 | This Is Stand-Up | Self |
| 2020 | Mentally Al | |
| 2019 | Tiny Changes | Self |
| 2019 | Laughing Matters | Herself |
| 2018 | Ralph brise l'Internet | Vanellope von Schweetz (voice) |
| 2018 | Seth Rogen's Hilarity for Charity | Self |
| 2018 | The Zen Diaries of Garry Shandling | Self |
| 2018 | Mister Rogers: It's You I Like | Self |
| 2018 | Origin Story | Herself |
| 2017 | La Bataille des sexes | Gladys Heldman |
| 2017 | Le livre d'Henry | Sheila |
| 2017 | Sarah Silverman: A Speck of Dust | Herself |
| 2017 | Michael Bolton's Big, Sexy Valentine's Day Special | Misty |
| 2017 | Punching Henry | Sharon Levine |
| 2017 | The Jim Jefferies Show | Self |
| 2017 | The Jim Jefferies Show | T5 Trailer Actor |
| 2017 | Dying Laughing | Herself |
| 2017 | I Love You, America | Self - Host |
| 2017 | The History of Comedy | Self |
| 2017 | Night of Too Many Stars: America Unites for Autism Programs | Self |
| 2016 | Popstar: Never Stop Never Stopping | Paula Klein |
| 2016 | Full Frontal with Samantha Bee | Self |
| 2016 | Chelsea | Self |
| 2016 | Lady Dynamite | Sarah Silverman |
| 2016 | 50 Years of Star Trek | Self |
| 2016 | The Last Laugh | Self |
| 2016 | Great Minds with Dan Harmon | Betsy Ross |
| 2016 | Bajillion Dollar Propertie$ | Zars St. Lars |
| 2016 | You Can Never Really Know Someone | Gretchen |
| 2015 | Ashby | June Wallis |
| 2015 | The Late Show with Stephen Colbert | Self |
| 2015 | I Smile Back | Laney Brooks |
| 2015 | Man Seeking Woman | Josh's Right Hand (voice) |
| 2015 | Tig | Self |
| 2015 | Gravy | Bethany |
| 2015 | $aving Dat Money | Sarah Silverman |
| 2014 | Mille et une façons de mourir dans l'ouest | Ruth |
| 2014 | Last Week Tonight with John Oliver | Self |
| 2014 | The Tonight Show Starring Jimmy Fallon | Self |
| 2014 | The Tonight Show Starring Jimmy Fallon | |
| 2014 | Late Night with Seth Meyers | |
| 2014 | Late Night with Seth Meyers | Self |
| 2014 | Harmontown | Self |
| 2014 | Women Aren't Funny | Herself |
| 2014 | Off Camera with Sam Jones | Self |
| 2014 | Rubberhead | Herself |
| 2014 | Cops Cum Dicks and Flying | Lieutenant Silverman |
| 2014 | The Unbelievably Sweet Alpacas | Happy |
| 2013 | Masters of Sex | Helen Schiff |
| 2013 | The Unbelievers | Self |
| 2013 | Comedy Central Roast of James Franco | Self |
| 2013 | Sarah Silverman: We Are Miracles | Herself |
| 2013 | Norm Macdonald Live | Self |
| 2013 | Fête des Pets | |
| 2013 | Sarah Silverman's Perfect Night | Herself |
| 2012 | Les Mondes de Ralph | Vanellope von Schweetz (voice) |
| 2012 | Comedians in Cars Getting Coffee | Self |
| 2012 | Comedy Bang! Bang! | Self |
| 2012 | Finding Your Roots | Self |
| 2012 | The Secret Policeman's Ball | Self |
| 2012 | The Bitter Buddha | Herself |
| 2012 | Inside Comedy | Self |
| 2011 | Les Muppets | Greeter |
| 2011 | Bob's Burgers | Ollie (voice) |
| 2011 | Bob's Burgers | Lead Singer (voice) |
| 2011 | Bob's Burgers | Ms. Schnur (voice) |
| 2011 | Bob's Burgers | Ollie (voice) / Carly (voice) / Meredith (voice) |
| 2011 | Take This Waltz | Geraldine |
| 2011 | Strange Powers: Stephin Merritt and the Magnetic Fields | Herself |
| 2011 | Give It Up for Greg Giraldo | Self |
| 2010 | Conan | Self |
| 2010 | Peep World | Cheri |
| 2010 | Saint John of Las Vegas | Jill |
| 2010 | I Am Comic | Self |
| 2010 | The Marriage Ref | Self - Panelist |
| 2010 | Backwash | Self |
| 2010 | The Buried Life | Self |
| 2009 | Drôle de monde | Sarah Silverman |
| 2009 | Une femme exemplaire | Stephanie Engler |
| 2009 | The League | Heather |
| 2009 | Watch What Happens Live with Andy Cohen | Self - Guest |
| 2009 | Funny People: Live | Self |
| 2008 | Childrens Hospital | Britches |
| 2008 | Comedy Central Roast of Bob Saget | Self |
| 2008 | Largo | Herself |
| 2008 | A Bad Situationist | Jamy Shonelike |
| 2008 | Match Game | Panelist |
| 2007 | Futurama : La Grande Aventure de Bender | Michelle (voice) |
| 2007 | The Graham Norton Show | Self |
| 2007 | Super High Me | Herself |
| 2007 | The Sarah Silverman Program. | Sarah Silverman |
| 2007 | The Sarah Silverman Program. | |
| 2007 | The Sarah Silverman Program. | Sarah Silverman (voice) |
| 2007 | Mr. Warmth: The Don Rickles Project | Self |
| 2007 | The Comedians of Comedy: Live at The Troubadour | Herself |
| 2007 | Fired! | Self |
| 2007 | Certifiably Jonathan | Self |
| 2006 | School for Scoundrels | Becky |
| 2006 | Comedy Central Roast of William Shatner | Self (archive footage) |
| 2006 | I Want Someone to Eat Cheese With | Beth |
| 2006 | The Secret Policeman's Ball: The Ball in the Hall | Self |
| 2005 | American Dad | Stripper (voice) |
| 2005 | Rent | Alexi Darling |
| 2005 | The Aristocrats | Self |
| 2005 | Sarah Silverman: Jesus Is Magic | Self |
| 2005 | Comedy Central Roast of Pamela Anderson | Self |
| 2005 | 8 Out of 10 Cats | Self |
| 2005 | Last Laugh '05 | Self |
| 2005 | Zach Galifianakis: Look Who it Isn't | Self |
| 2005 | Too Late with Adam Carolla | |
| 2005 | The Most Extraordinary Space Investigations | Jelly Roll |
| 2005 | Channel 101: The Musical | Herself |
| 2004 | Drawn Together | Bleh (voice) |
| 2004 | Hair High | Cherri (voice) |
| 2004 | Tom Goes to the Mayor | Barb Dunderbarn (voice) |
| 2004 | Stories of Lost Souls | Herself |
| 2004 | The Friday the 13th Chronicles | Self |
| 2004 | Pilot Season | Susan Underman |
| 2003 | L'école du rock | Patty Di Marco |
| 2003 | Real Time with Bill Maher | Self |
| 2003 | Jimmy Kimmel Live! | |
| 2003 | Jimmy Kimmel Live! | Self |
| 2003 | Supermarket | Self |
| 2003 | Celebrity Poker Showdown | Self |
| 2003 | Comedy Central Roasts | Self |
| 2002 | Monk | Marci Maven |
| 2002 | Run Ronnie Run | Network Executive #3 |
| 2002 | Crank Yankers | |
| 2002 | Greg the Bunny | Alison Kaiser |
| 2002 | Tough Crowd with Colin Quinn | |
| 2002 | Saddle Rash | Hanna Headstrong (voice) |
| 2002 | Saddle Rash | |
| 2001 | Évolution | Denise |
| 2001 | Heartbreakers | Linda |
| 2001 | Say It Isn't So | Gina |
| 2001 | The N.Y. Friars Club Roast of Hugh Hefner | Self |
| 2000 | The Way of the Gun | Raving Bitch |
| 2000 | What Planet Are You From? | Woman on plane |
| 2000 | Screwed | Hillary |
| 2000 | Manhattan, AZ | Dakota |
| 1999 | Futurama | Michelle (voice) |
| 1999 | The Bachelor | Carolyn |
| 1999 | WWE SmackDown | Self |
| 1999 | Late Last Night | Jen |
| 1998 | Marie a un je-ne-sais-quoi | Brenda |
| 1998 | Bulworth | 2nd American Politics Assistant |
| 1998 | Overnight Delivery | Turran |
| 1998 | V.I.P. | Lucy Stanton |
| 1998 | Hollywood Squares | Self - Panelist |
| 1998 | Saturday Night Live: A Tribute to Chris Farley | Self |
| 1997 | The View | Self |
| 1997 | The View | Self - Guest |
| 1997 | Who's the Caboose? | Susan |
| 1996 | The Daily Show | Self - Guest Host |
| 1995 | Star Trek: Voyager | Rain Robinson |
| 1995 | JAG | Tina Schiparelli |
| 1995 | Mr. Show with Bob and David | Various |
| 1995 | Mr. Show with Bob and David | Jeepers Creepers Dancer |
| 1995 | The Naked Truth | Ali Walters |
| 1995 | Brotherly Love | Rosa |
| 1993 | Frasier | Jane |
| 1993 | Droopy, Master Detective | Melody WOOO-WOOO Stardust (voice) |
| 1992 | The Larry Sanders Show | Wendy Traston |
| 1992 | The Larry Sanders Show | Sarah Silverman |
| 1992 | MTV Movie & TV Awards | Self - Host |
| 1990 | Caesar's Salad | Smoothies Keyboard |
| 1989 | Les Simpson | Rachel, Lisa's Imaginary Friend (voice) |
| 1989 | Les Simpson | Sarah Silverman (voice) |
| 1989 | Les Simpson | Nikki McKenna (voice) |
| 1989 | Seinfeld | Emily |
| 1975 | Saturday Night Live | Self - Host |
| 1975 | Saturday Night Live | Self - Various Characters |
