| — | Time Belt | Computerman |
| — | Anaconda | |
| — | Stepdude | Sherman |
| — | Micronations | |
| 2025 | A Minecraft Movie | Steve |
| 2024 | Kung Fu Panda 4 | Po (voice) |
| 2024 | Borderlands | Claptrap (voice) |
| 2024 | ZEF - The Story of Die Antwoord | Self |
| 2024 | Dueling Dumplings | Po (voice) |
| 2023 | The Super Mario Bros. Movie | Bowser (voice) |
| 2023 | History of the World: Part II | Joseph Stalin |
| 2023 | The Video Game Crash of 1983 | Self |
| 2023 | Tenacious D Live Rock am Ring | Self |
| — | Tenacious D: Live at the Mann Center | Self |
| — | Oh Hell No | Sherman |
| 2023 | Tenacious D: Rock Am Ring 2023 | Self |
| — | The Glorious Octagon Of Destiny | Self |
| — | Making Of School of Rock | Self |
| — | Dear Santa | Satan |
| 2023 | Free LSD | (Special Appearance) |
| 2023 | Tenacious D and the Spicy Meatball Tour | JB |
| 2022 | Weird: The Al Yankovic Story | Wolfman Jack |
| 2022 | Apollo 10½: A Space Age Childhood | Grown Up Stan (voice) |
| 2022 | Kung Fu Panda: The Dragon Knight | Po (voice) |
| 2022 | Dio: Dreamers Never Die | Self |
| 2022 | Big Nate | Brad Gunter (voice) |
| 2022 | How Did We Get Here? | Self (archive footage) |
| 2021 | Celebrity Wheel of Fortune | Self - Contestant |
| 2021 | 2021 Rock & Roll Hall of Fame Induction Ceremony | Self |
| 2020 | One World: Together at Home | Self |
| 2020 | Happy Happy Joy Joy: The Ren & Stimpy Story | Self |
| 2020 | Celebrity Escape Room | Self - Game Master |
| 2020 | Home Movie: The Princess Bride | Westley |
| 2020 | Dear Class of 2020 | Self |
| 2020 | Cup of Joe | Self |
| 2020 | Feeding America Comedy Festival | Self |
| 2020 | This is (not) the greatest song in the world. | JB |
| 2019 | The Mandalorian | Captain Bombardier |
| 2019 | Jumanji: The Next Level | Professor Sheldon 'Shelly' Oberon |
| 2019 | The Kelly Clarkson Show | |
| 2019 | JablinskiGames | Self |
| 2019 | Tenacious D: Rock In Rio 2019 | Self |
| 2018 | The House with a Clock in Its Walls | Jonathan Barnavelt |
| 2018 | Goosebumps 2: Haunted Halloween | R. L. Stine (uncredited) |
| 2018 | Don't Worry, He Won't Get Far on Foot | Dexter |
| 2018 | Eli Roth's History of Horror | |
| 2018 | The Joel McHale Show with Joel McHale | Self - Special Guest |
| 2018 | Kung Fu Panda: The Emperor's Quest | Po (voice) |
| 2018 | The Insufferable Groo | Self |
| 2018 | Tenacious D in Post-Apocalypto | JB |
| 2018 | The Unexpected Race | Sheriff |
| 2017 | Jumanji: Welcome to the Jungle | Professor Sheldon 'Shelly' Oberon |
| 2017 | The Polka King | Jan Lewan |
| 2017 | The Words That Built America | Self - Reader - Declaration of Independence |
| 2017 | The Russell Howard Hour | Self |
| 2017 | The Gong Show | Self - Judge |
| 2017 | Tommy Can`t Sleep | Big Tommy |
| 2016 | Kung Fu Panda 3 | Po (voice) |
| 2016 | Kung Fu Panda: Secrets of the Scroll | Po (voice) |
| 2016 | Full Frontal with Samantha Bee | Self |
| 2016 | Richard Linklater: Dream Is Destiny | Self |
| 2016 | Join or Die with Craig Ferguson | |
| 2016 | Great Minds with Dan Harmon | Ludwig van Beethoven |
| 2015 | Goosebumps | R.L. Stine |
| 2015 | The Late Show with Stephen Colbert | Self |
| 2015 | The D Train | Dan Landsman |
| 2015 | The Brink | Alex Talbot |
| 2015 | Documentary Now! | Jamison Friend |
| 2015 | Another Period | Dan Ringley |
| 2015 | Hot Ones | Self |
| 2015 | StarTalk with Neil deGrasse Tyson | Self |
| 2015 | Sesame Street: Play All Day with Elmo! | Self |
| 2014 | Sex Tape | YouPorn Owner (uncredited) |
| 2014 | The Tonight Show Starring Jimmy Fallon | Self |
| 2014 | Late Night with Seth Meyers | Self |
| 2014 | Harmontown | Self |
| 2014 | Welcome to Sweden | Self |
| 2014 | 21 Years: Richard Linklater | Self - Actor |
| 2014 | Heaven Adores You | Self |
| 2014 | The Sheik | |
| 2014 | The Concert for Valor | Self |
| 2014 | Off Camera with Sam Jones | Self |
| 2013 | Rick and Morty | Lithdor (voice) |
| 2013 | Drunk History | William Mulholland |
| 2013 | Drunk History | Vincenzo Peruggia |
| 2013 | Drunk History | Elvis Presley |
| 2013 | Metalocalypse: The Doomstar Requiem - A Klok Opera | Dethklok's Original Manager / Fat Fan (voice) |
| 2013 | The Birthday Boys | |
| 2013 | Radio Disney Music Awards | Self - Presenter |
| 2012 | Bernie | Bernie Tiede |
| 2012 | The Eric Andre Show | Self |
| 2012 | Dreamworks Holiday Classics | Po (voice) |
| 2012 | Good Mythical Morning | Self |
| 2012 | Comedy Bang! Bang! | Self |
| 2012 | Girl & Chocolate - Pretty Sweet | Self |
| 2012 | Double Fine Adventure | Self |
| 2012 | The Roadie | JB |
| 2011 | Kung Fu Panda 2 | Po (voice) |
| 2011 | The Muppets | Jack Black (uncredited) |
| 2011 | The Big Year | Brad Harris |
| 2011 | Kung Fu Panda: Secrets of the Masters | Po (voice) |
| 2011 | Conan O'Brien Can't Stop | Self |
| 2011 | Fight for Your Right Revisited | MCA (B-Boys 2) |
| 2011 | Brain Games | Self |
| 2010 | Gulliver's Travels | Lemuel Gulliver |
| 2010 | Kung Fu Panda Holiday | Po (voice) |
| 2010 | Conan | Self |
| 2010 | Rush: Beyond The Lighted Stage | Self |
| 2010 | Tenacious D Live at BlizzCon 2010 | as JB |
| 2009 | Year One | Zed |
| 2009 | Community | Buddy |
| 2009 | Watch What Happens Live with Andy Cohen | Self - Guest |
| 2009 | Chopped | Self |
| 2009 | The Jay Leno Show | Self |
| 2009 | We Are One: The Obama Inaugural Celebration at the Lincoln Memorial | Self |
| 2008 | Kung Fu Panda | Po (voice) |
| 2008 | Tropic Thunder | Jeff Portnoy |
| 2008 | Be Kind Rewind | Jerry |
| 2008 | Kung Fu Panda: Secrets of the Furious Five | Po (voice) |
| 2008 | Tropic Thunder: Rain of Madness | Jeff Portnoy |
| 2008 | Prop 8: The Musical | Jesus Christ |
| 2008 | Tenacious D: The Complete Masterworks 2 | Self |
| 2008 | D Tour: A Tenacious Documentary | Self |
| 2008 | Water And Power | The Mayor |
| 2008 | VH1 Rock Honors: The Who | Self |
| 2007 | iCarly | Aspartamay |
| 2007 | Walk Hard: The Dewey Cox Story | Paul McCartney (uncredited) |
| 2007 | Margot at the Wedding | Malcolm |
| 2007 | The Graham Norton Show | Self |
| 2007 | The Naked Trucker and T-Bones Show | |
| 2007 | Acceptable.tv | |
| 2007 | Acceptable.tv | Self / Cop / Story Wizard |
| 2007 | The Making of 'The Pick of Destiny' | Self |
| 2007 | Tenacious D: For the Ladies | JB |
| 2006 | The Holiday | Miles Dumont |
| 2006 | Nacho Libre | Nacho |
| 2006 | Tenacious D in The Pick of Destiny | JB |
| 2006 | Awesometown | George Washington |
| 2006 | Recreating the Eighth Wonder: The Making of 'King Kong' | Self |
| 2006 | Tenacious D: Time Fixers | JB |
| 2006 | The Eighth Blunder of the World | Self |
| 2006 | Exposure | Dan Harmon |
| 2005 | King Kong | Carl Denham |
| 2005 | The Office | Sam |
| 2005 | The Late Late Show with Craig Ferguson | Self |
| 2005 | King Kong: Peter Jackson's Production Diaries | Self |
| 2005 | 무한도전 | Self |
| 2005 | Club Oscar | Lenny (voice) |
| 2005 | Made in Hollywood | Self |
| 2005 | The Showbiz Show with David Spade | |
| 2005 | Earth to America | Self |
| 2005 | A Concert for Hurricane Relief | Self - Presenter |
| 2004 | Shark Tale | Lenny (voice) |
| 2004 | Anchorman: The Legend of Ron Burgundy | Motorcyclist |
| 2004 | Envy | Nick Vanderpark |
| 2004 | Tom Goes to the Mayor | Trapper JB (voice) |
| 2004 | Cracking Up | |
| 2004 | The Present | Self |
| 2004 | Live at Johnny's | |
| 2004 | Laser Fart | The Elegant Hunter |
| 2004 | Channel 101 | Self - Host |
| 2003 | School of Rock | Dewey Finn |
| 2003 | The Ellen DeGeneres Show | Self |
| 2003 | Jimmy Kimmel Live! | |
| 2003 | Jimmy Kimmel Live! | Self - Emmys segment |
| 2003 | Melvin Goes to Dinner | Mental Patient (uncredited) |
| 2003 | Tenacious D: The Complete Masterworks | Self |
| 2003 | Celebrities Uncensored | Self |
| 2003 | Computerman | Computerman |
| 2003 | Tenacious D: In the Studio | Self |
| 2002 | Ice Age | Zeke (voice) |
| 2002 | Orange County | Lance Brumder |
| 2002 | American Idol | Self |
| 2002 | Clone High | Pusher / Larry Hardcore (voice) |
| 2002 | Run Ronnie Run | Lead Chimney Sweep |
| 2002 | Last Call with Carson Daly | Self |
| 2002 | Shallow Hal: Seeing Through the Make-up | Self |
| 2002 | HypaSpace | Self |
| 2002 | Lord of the Piercing | Jack the Elf |
| 2002 | Tenacious D: Live in London | Self |
| 2002 | Tenacious D: Rock Star Sperm for Sale | JB |
| 2002 | Tenacious D: Butt Baby | JB |
| 2002 | Icons | |
| 2002 | The Lewis Lectures | Lewis (voice) |
| 2001 | Shallow Hal | Hal |
| 2001 | Saving Silverman | J.D. McNugent |
| 2001 | Friday Night with Jonathan Ross | Self |
| 2001 | Reel Comedy: Shallow Hal | Self |
| 2001 | The Andy Dick Show | J.D |
| 2001 | Being 'Shallow Hal' | Self |
| 2001 | Tenacious D: JB's BJ | JB |
| 2000 | High Fidelity | Barry Judd |
| 2000 | Jesus' Son | Georgie |
| 1999 | Cradle Will Rock | Sid |
| 1999 | The Love Letter | Fisherman (uncredited) |
| 1999 | Heat Vision and Jack | Jack Austin |
| 1999 | Heat Vision and Jack | Jack Austin |
| 1998 | Enemy of the State | Fiedler |
| 1998 | I Still Know What You Did Last Summer | Titus Telesco (uncredited) |
| 1998 | Will & Grace | Dr. Isaac Hershberg |
| 1998 | Bongwater | Devlin |
| 1998 | Johnny Skidmarks | Jerry |
| 1997 | The Jackal | Ian Lamont |
| 1997 | The View | Self |
| 1997 | Tenacious D | Jack 'JB' Black |
| 1996 | Mars Attacks! | Billy Glenn Norris |
| 1996 | The Cable Guy | Rick |
| 1996 | The Fan | Broadcast Technician |
| 1996 | The Daily Show | Self |
| 1996 | Bio-Dome | Tenacious D |
| 1996 | E! True Hollywood Story | |
| 1996 | Crossworlds | Steve |
| 1995 | Waterworld | Pilot |
| 1995 | Dead Man Walking | Craig Poncelet |
| 1995 | Bye Bye Love | DJ at Party |
| 1995 | Mr. Show with Bob and David | Jeepers Creepers |
| 1995 | Mr. Show with Bob and David | Expert |
| 1995 | Mr. Show with Bob and David | Gay Guy / Moviegoer |
| 1995 | Mr. Show with Bob and David | Farmer / Satan / God |
| 1995 | The Single Guy | Randy |
| 1995 | Pride & Joy | Man |
| 1994 | The NeverEnding Story III | Slip |
| 1994 | Touched by an Angel | Monte |
| 1994 | Space Ghost Coast to Coast | |
| 1994 | Blind Justice | Private |
| 1994 | The Innocent | Marty Prago |
| 1994 | All-American Girl | Tommy |
| 1994 | Monty | Doug |
| 1993 | Demolition Man | Wasteland Scrap |
| 1993 | The X-Files | Bart 'Zero' Liquori |
| 1993 | Late Night with Conan O'Brien | Self - Guest |
| 1993 | Airborne | Augie |
| 1993 | Marked for Murder | Car Thief |
| 1992 | Bob Roberts | Roger Davis |
| 1992 | The Tonight Show with Jay Leno | |
| 1992 | Picket Fences | Curtis Williams |
| 1992 | The Golden Palace | Cab Driver |
| 1992 | MTV Movie & TV Awards | Self |
| 1992 | Great Scott! | Ray |
| 1990 | Northern Exposure | Kevin Wilkins |
| 1989 | The Simpsons | Milo (voice) |
| 1989 | Life Goes On | Skinhead |
| 1988 | This Morning | Self |
| 1987 | Kids' Choice Awards | Host |
| 1987 | Too Far from the Norm | Rick |
| 1984 | MTV Video Music Awards | Self - Host |
| 1984 | The New Leave It to Beaver | Nick |
| 1981 | The Fall Guy | Chuck |
| 1975 | Saturday Night Live | Self - Host |
| 1975 | Saturday Night Live | Self - Musical Guest |
| 1975 | Saturday Night Live | Self - Cameo (uncredited) |
| 1953 | The Oscars | Self |
